Product Description
ATRN Antibody (N-term) [APG02173G] | Leading Biology
Product Category: Polyclonal Antibodies
Host: Rabbit
Species Reactivity: H
Specificity: This ATRN antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 32-66 amino acids from the N-terminal region of human ATRN.
Cellular Localisation: [Isoform 1]: Cell membrane; Single-pass type I membrane protein [Isoform 3]: Secreted
Molecular Weight: 158537
Clone: Polyclonal
Gene Name: ATRN
Gene ID: 8455
Function: Involved in the initial immune cell clustering during inflammatory response and may regulate chemotactic activity of chemokines. May play a role in melanocortin signaling pathways that regulate energy homeostasis and hair color. Low-affinity receptor for agouti (By similarity) . Has a critical role in normal myelination in the central nervous system (By similarity) .
Summary: Tissue Location: Isoform 2 is detected in plasma (at protein level) . Expressed and secreted by activated T-lymphocytes. Expressed at low to moderate levels in peripheral blood leukocytes, spleen, lymph node, tonsil, bone marrow and fetal liver. At very low levels found in thymus. Isoform 2 is the major isoform in peripheral blood leukocytes
Form: N/A
Storage: Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Application: WB
Dilution: WB--1:1000
Synonyms: Attractin, DPPT-L, Mahogany homolog, ATRN, KIAA0548, MGCA