Product Description
C14orf179 Antibody (Center) [APR15189G] | Leading Biology
Product Category: Polyclonal Antibodies
Host: Rabbit
Species Reactivity: H, M
Specificity: This C14orf179 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 145-171 amino acids from the Central region of human C14orf179.
Cellular Localisation: Cytoplasm, cytoskeleton. Cell projection, cilium Note=Associated with microtubules (PubMed:22361696) . Localized at the distal tip of the cilium (PubMed:28973684)
Molecular Weight: 23529
Clone: Polyclonal
Gene Name: IFT43 (HGNC:29669)
Gene ID: 112752
Function: As a component of IFT complex A (IFT-A), a complex required for retrograde ciliary transport and entry into cilia of G protein- coupled receptors (GPCRs), it is involved in ciliogenesis (PubMed:28400947, PubMed:28973684) . Involved in retrograde ciliary transport along microtubules from the ciliary tip to the base (PubMed:21378380) .
Summary: Tissue Location: Expressed in the retina, predominantly in the photoreceptor outer segment.
Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Application: WB, IHC-P, FC
Dilution: WB--1:1000 IHC-P--1:100~500 FC--1:10~50
Synonyms: Intraflagellar transport protein 43 homolog, IFT43, C14orf179