Product Description
DRAGON (RGMB) Antibody (Center) [APR11799G] | Leading Biology
Product Category: Polyclonal Antibodies
Host: Rabbit
Species Reactivity: H, M
Specificity: This DRAGON (RGMB) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 278-309 amino acids from the Central region of human DRAGON (RGMB) .
Cellular Localisation: Cell membrane {ECO:0000250|UniProtKB:Q7TQ33}; Lipid-anchor, GPI-anchor {ECO:0000250|UniProtKB:Q7TQ33}. Membrane raft {ECO:0000250|UniProtKB:Q7TQ33}
Molecular Weight: 47547
Clone: Polyclonal
Gene Name: RGMB {ECO:0000303|PubMed:19324014, ECO:0000312|HGNC:HGNC:26896}
Gene ID: 285704
Function: Member of the repulsive guidance molecule (RGM) family that contributes to the patterning of the developing nervous system (By similarity) . Acts as a bone morphogenetic protein (BMP) coreceptor that potentiates BMP signaling (By similarity) . Promotes neuronal adhesion (By similarity) . May inhibit neurite outgrowth.
Summary: N/A
Form: Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, followed by dialysis against PBS.
Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Application: WB, IHC-P
Dilution: WB--1:1000 IHC-P--1:100~500
Synonyms: RGM domain family member B, DRG11-responsive axonal guidance and outgrowth of neurite, DRAGON, RGMB