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![Phospho-Bad (S75) Antibody [APR09142G]](https://cdn11.bigcommerce.com/s-452hpg8iuh/images/stencil/1280x1280/products/866871/1158938/logo__92149.1659788186__53461.1659863405.png?c=2 "Phospho-Bad (S75) Antibody [APR09142G]"){kind=logo}
![Phospho-Bad (S75) Antibody [APR09142G]](https://cdn11.bigcommerce.com/s-452hpg8iuh/images/stencil/100x100/products/866871/1158938/logo__92149.1659788186__53461.1659863405.png?c=2 "Phospho-Bad (S75) Antibody [APR09142G]"){kind=logo}
Product Description
Phospho-Bad (S75) Antibody [APR09142G] | Leading Biology
Product Category: Polyclonal Antibodies
Host: Rabbit
Species Reactivity: H
Specificity: This Bad Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S75 of human Bad.
Cellular Localisation: Mitochondrion outer membrane. Cytoplasm {ECO:0000250|UniProtKB:Q61337}. Note=Colocalizes with HIF3A in the cytoplasm (By similarity) . Upon phosphorylation, locates to the cytoplasm. {ECO:0000250|UniProtKB:Q61337}
Molecular Weight: 18392
Clone: Polyclonal
Gene Name: BAD
Gene ID: 572
Function: Promotes cell death. Successfully competes for the binding to Bcl-X (L), Bcl-2 and Bcl-W, thereby affecting the level of heterodimerization of these proteins with BAX. Can reverse the death repressor activity of Bcl-X (L), but not that of Bcl-2 (By similarity) . Appears to act as a link between growth factor receptor signaling and the apoptotic pathways.
Summary: Tissue Location: Expressed in a wide variety of tissues.
Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Application: WB, IHC-P
Dilution: WB--1:1000 IHC-P--1:100~500
Synonyms: Bcl2-associated agonist of cell death, BAD, Bcl-2-binding component 6, Bcl-2-like protein 8, Bcl2-L-8, Bcl-xL/Bcl-2-associated death promoter, Bcl2 antagonist of cell death, BAD, BBC6, BCL2L8
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