Product Description
TGFB1 Antibody (N-term) [APR07196G] | Leading Biology
Product Category: Polyclonal Antibodies
Host: Rabbit
Species Reactivity: H, M
Specificity: This TGFB1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 30-50 amino acids of human TGFB1.
Cellular Localisation: [Latency-associated peptide]: Secreted, extracellular space, extracellular matrix
Molecular Weight: 44341
Clone: Polyclonal
Gene Name: TGFB1 (HGNC:11766)
Gene ID: 7040
Function: Transforming growth factor beta-1 proprotein: Precursor of the Latency-associated peptide (LAP) and Transforming growth factor beta-1 (TGF-beta-1) chains, which constitute the regulatory and active subunit of TGF-beta-1, respectively.
Summary: Tissue Location: Highly expressed in bone (PubMed:11746498, PubMed:17827158) . Abundantly expressed in articular cartilage and chondrocytes and is increased in osteoarthritis (OA) (PubMed:11746498, PubMed:17827158) . Colocalizes with ASPN in chondrocytes within OA lesions of articular cartilage (PubMed:17827158)
Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Application: WB
Dilution: WB--1:2000
Synonyms: Transforming growth factor beta-1, TGF-beta-1, Latency-associated peptide, LAP, TGFB1, TGFB