Product Description
Twinfilin-2 (PTK9L) Antibody (C-term) [APR14076G] | Leading Biology
Product Category: Polyclonal Antibodies
Host: Rabbit
Species Reactivity: H
Specificity: This Twinfilin-2 (PTK9L) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 320-349 amino acids from the C-terminal region of human Twinfilin-2 (PTK9L) .
Cellular Localisation: Cytoplasm, cytoskeleton. Cytoplasm, perinuclear region. Cell projection, stereocilium. Note=Perinuclear and G-actin-rich cortical actin structure sublocalization
Molecular Weight: 39548
Clone: Polyclonal
Gene Name: TWF2
Gene ID: 11344
Function: Actin-binding protein involved in motile and morphological processes. Inhibits actin polymerization, likely by sequestering G- actin. By capping the barbed ends of filaments, it also regulates motility. Seems to play an important role in clathrin-mediated endocytosis and distribution of endocytic organelles. May play a role in regulating the mature length of the middle and short rows of stereocilia (By similarity) .
Summary: Tissue Location: Ubiquitously expressed (at protein level) .
Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Application: WB
Dilution: WB--1:1000
Synonyms: Twinfilin-2, A6-related protein, hA6RP, Protein tyrosine kinase 9-like, Twinfilin-1-like protein, TWF2, PTK9L