Product Description
PAX2 Antibody | 31-206 | ProSci
Host: Rabbit
Reactivity: Human
Homology: N/A
Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human PAX2.
Research Area: Transcription, Cancer
Tested Application: E, WB, IHC
Application: PAX2 antibody can be used for detection of PAX2 by ELISA at 1:312500. PAX2 antibody can be used for detection of PAX2 by western blot at 1.0 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50, 000 - 100, 000.
Specificiy: N/A
Positive Control 1: Cat. No. 1219 - MCF7 Cell Lysate
Positive Control 2: N/A
Positive Control 3: N/A
Positive Control 4: N/A
Positive Control 5: N/A
Positive Control 6: N/A
Molecular Weight: 42 kDa, 44 kDa, 42 kDa
Validation: N/A
Isoform: N/A
Purification: Antibody is purified by Protein A/G affinity chromatography method.
Clonality: Polyclonal
Clone: N/A
Isotype: N/A
Conjugate: Unconjugated
Physical State: Liquid
Buffer: Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Concentration: batch dependent
Storage Condition: For short periods of storage (days) store at 4˚C. For longer periods of storage, store PAX2 antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.
Alternate Name: PAX2, PAPRS
User Note: Optimal dilutions for each application to be determined by the researcher.
BACKGROUND: PAX2 encodes paired box gene 2, one of many human homologues of the Drosophila melanogaster gene prd. The central feature of this transcription factor gene family is the conserved DNA-binding paired box domain. PAX2 is believed to be a target of transcriptional supression by the tumor supressor gene WT1. Mutations within PAX2 have been shown to result in optic nerve colobomas and renal hypoplasia.