Product Description
ATP6V1E1 Antibody | 19-150 | ProSci
Host: Rabbit
Reactivity: Human, Mouse, Rat
Homology: N/A
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 77-226 of human ATP6V1E1 (NP_001687.1) .
Research Area: Cancer, Signal Transduction
Tested Application: WB, IHC
Application: WB: 1:1000 - 1:2000
IHC: 1:50 - 1:200
Specificiy: N/A
Positive Control 1: U-87MG
Positive Control 2: DU145
Positive Control 3: LO2
Positive Control 4: Mouse brain
Positive Control 5: Mouse kidney
Positive Control 6: Mouse liver
Molecular Weight: Observed: 35kDa
Validation: N/A
Isoform: N/A
Purification: Affinity purification
Clonality: Polyclonal
Clone: N/A
Isotype: IgG
Conjugate: Unconjugated
Physical State: Liquid
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Concentration: N/A
Storage Condition: Store at -20˚C. Avoid freeze / thaw cycles.
Alternate Name: ARCL2C, ATP6E, ATP6E2, ATP6V1E, P31, Vma4, V-type proton ATPase subunit E 1, ATPase, H+ transporting, lysosomal 31kDa, V1 subunit E1, H (+) -transporting two-sector ATPase, 31kDa subunit, H+-transporting ATP synthase chain E, vacuolar, V-ATPase 31 kDa subunit, V-ATPase subunit E 1, V-ATPase, subunit E, vacuolar proton pump subunit E 1
User Note: Optimal dilutions for each application to be determined by the researcher.
BACKGROUND: This gene encodes a component of vacuolar ATPase (V-ATPase) , a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A, three B, and two G subunits, as well as a C, D, E, F, and H subunit. The V1 domain contains the ATP catalytic site. This gene encodes alternate transcriptional splice variants, encoding different V1 domain E subunit isoforms. Pseudogenes for this gene have been found in the genome.