Product Description
B4GALT3 Antibody | 16-988 | ProSci
Host: Rabbit
Reactivity: Human, Mouse, Rat
Homology: N/A
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 40-150 of human B4GALT3 (NP_003770.1) .
Research Area: Other
Tested Application: WB, IHC
Application: WB: 1:500 - 1:2000
IHC: 1:100 - 1:200
Specificiy: N/A
Positive Control 1: Mouse heart
Positive Control 2: Rat spleen
Positive Control 3: Rat kidney
Positive Control 4: N/A
Positive Control 5: N/A
Positive Control 6: N/A
Molecular Weight: Observed: 44kDa
Validation: N/A
Isoform: N/A
Purification: Affinity purification
Clonality: Polyclonal
Clone: N/A
Isotype: IgG
Conjugate: Unconjugated
Physical State: Liquid
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Concentration: N/A
Storage Condition: Store at -20˚C. Avoid freeze / thaw cycles.
Alternate Name: beta4Gal-T3, beta-1, 4-galactosyltransferase 3, N-acetyllactosamine synthase, UDP-Gal:beta-GlcNAc beta-1, 4-galactosyltransferase 3, UDP-Gal:betaGlcNAc beta 1, 4- galactosyltransferase, polypeptide 3, UDP-galactose:beta-N-acetylglucosamine beta-1, 4-galactosyltransferase 3, b4Gal-T3, beta-1, 4-GalTase 3, beta-N-acetylglucosaminyl-glycolipid beta-1, 4-galactosyltransferase 3, beta-N-acetylglucosaminylglycopeptide beta-1, 4-galactosyltransferase, epididymis secretory sperm binding protein, nal synthase
User Note: Optimal dilutions for each application to be determined by the researcher.
BACKGROUND: This gene is one of seven beta-1, 4-galactosyltransferase (beta4GalT) genes. They encode type II membrane-bound glycoproteins that appear to have exclusive specificity for the donor substrate UDP-galactose; all transfer galactose in a beta1, 4 linkage to similar acceptor sugars: GlcNAc, Glc, and Xyl. Each beta4GalT has a distinct function in the biosynthesis of different glycoconjugates and saccharide structures. As type II membrane proteins, they have an N-terminal hydrophobic signal sequence that directs the protein to the Golgi apparatus and which then remains uncleaved to function as a transmembrane anchor. By sequence similarity, the beta4GalTs form four groups: beta4GalT1 and beta4GalT2, beta4GalT3 and beta4GalT4, beta4GalT5 and beta4GalT6, and beta4GalT7. This gene encodes an enzyme that may be mainly involved in the synthesis of the first N-acetyllactosamine unit of poly-N-acetyllactosamine chains. Multiple alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Dec 2010]