Product Description
DICER1 Antibody | 19-979 | ProSci
Host: Rabbit
Reactivity: Human, Mouse, Rat
Homology: N/A
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1200-1460 of human DICER1 (NP_085124.2) .
Research Area: Other
Tested Application: WB, IHC, IF
Application: WB: 1:500 - 1:1000
IHC: 1:50 - 1:200
IF: 1:100 - 1:200
Specificiy: N/A
Positive Control 1: NCI-H460
Positive Control 2: U-251MG
Positive Control 3: HepG2
Positive Control 4: MCF7
Positive Control 5: N/A
Positive Control 6: N/A
Molecular Weight: Observed: 250kDa
Validation: N/A
Isoform: N/A
Purification: Affinity purification
Clonality: Polyclonal
Clone: N/A
Isotype: IgG
Conjugate: Unconjugated
Physical State: Liquid
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Concentration: N/A
Storage Condition: Store at -20˚C. Avoid freeze / thaw cycles.
Alternate Name: DCR1, Dicer, Dicer1e, GLOW, HERNA, K12H4.8-LIKE, MNG1, RMSE2, endoribonuclease Dicer, Dicer1, Dcr-1 homolog, dicer 1, double-stranded RNA-specific endoribonuclease, dicer 1, ribonuclease type III, helicase MOI, helicase with RNAse motif
User Note: Optimal dilutions for each application to be determined by the researcher.
BACKGROUND: This gene encodes a protein possessing an RNA helicase motif containing a DEXH box in its amino terminus and an RNA motif in the carboxy terminus. The encoded protein functions as a ribonuclease and is required by the RNA interference and small temporal RNA (stRNA) pathways to produce the active small RNA component that represses gene expression. Alternative splicing results in multiple transcript variants.