Product Description
EIF4A3 Antibody | 19-347 | ProSci
Host: Rabbit
Reactivity: Human, Mouse, Rat
Homology: N/A
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-210 of human EIF4A3 (NP_055555.1) .
Research Area: Other
Tested Application: WB, IHC
Application: WB: 1:1000 - 1:3000
IHC: 1:50 - 1:200
Specificiy: N/A
Positive Control 1: A-431
Positive Control 2: Jurkat
Positive Control 3: HeLa
Positive Control 4: A-549
Positive Control 5: NIH/3T3
Positive Control 6: Mouse spleen
Molecular Weight: Observed: 47kDa
Validation: N/A
Isoform: N/A
Purification: Affinity purification
Clonality: Polyclonal
Clone: N/A
Isotype: IgG
Conjugate: Unconjugated
Physical State: Liquid
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Concentration: N/A
Storage Condition: Store at -20˚C. Avoid freeze / thaw cycles.
Alternate Name: DDX48, DDX48, MUK34, NUK34, NMP265, eIF4AIII
User Note: Optimal dilutions for each application to be determined by the researcher.
BACKGROUND: This gene encodes a member of the DEAD box protein family. DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD) , are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure, such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. The protein encoded by this gene is a nuclear matrix protein. Its amino acid sequence is highly similar to the amino acid sequences of the translation initiation factors eIF4AI and eIF4AII, two other members of the DEAD box protein family.