Product Description
FBXL14 Antibody | 18-127 | ProSci
Host: Rabbit
Reactivity: Human, Mouse, Rat, Other
Homology: N/A
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-418 of human FBXL14 (NP_689654.1) .
Research Area: Other
Tested Application: WB
Application: WB: 1:500 - 1:2000
Specificiy: N/A
Positive Control 1: A-431
Positive Control 2: HepG2
Positive Control 3: Mouse thymus
Positive Control 4: Mouse spleen
Positive Control 5: Mouse brain
Positive Control 6: Rat thymus
Molecular Weight: Observed: 46kDa
Validation: N/A
Isoform: N/A
Purification: Affinity purification
Clonality: Polyclonal
Clone: N/A
Isotype: IgG
Conjugate: Unconjugated
Physical State: Liquid
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Concentration: N/A
Storage Condition: Store at -20˚C. Avoid freeze / thaw cycles.
Alternate Name: F-box/LRR-repeat protein 14, F-box and leucine-rich repeat protein 14, FBXL14, FBL14
User Note: Optimal dilutions for each application to be determined by the researcher.
BACKGROUND: Members of the F-box protein family, such as FBXL14, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434) , cullin (see CUL1; MIM 603134) , and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004 [PubMed 15520277]) .[supplied by OMIM, Mar 2008]