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Product Description
HADHA Antibody, KO Validated | 19-605 | ProSci
Host: Rabbit
Reactivity: Human, Mouse, Rat
Homology: N/A
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 484-763 of human HADHA (NP_000173.2) .
Research Area: Cancer, Signal Transduction
Tested Application: WB, IF, IP
Application: WB: 1:500 - 1:2000
IF: 1:50 - 1:200
IP: 1:50 - 1:100
Specificiy: N/A
Positive Control 1: K-562
Positive Control 2: THP-1
Positive Control 3: SW480
Positive Control 4: PC-3
Positive Control 5: HeLa
Positive Control 6: Mouse intestine
Molecular Weight: Observed: 82kDa
Validation: Antibody is Knockout validated.
Isoform: N/A
Purification: Affinity purification
Clonality: Polyclonal
Clone: N/A
Isotype: IgG
Conjugate: Unconjugated
Physical State: Liquid
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Concentration: N/A
Storage Condition: Store at -20˚C. Avoid freeze / thaw cycles.
Alternate Name: Trifunctional enzyme subunit alpha, mitochondrial, 78 kDa gastrin-binding protein, TP-alpha, Long-chain enoyl-CoA hydratase, Long chain 3-hydroxyacyl-CoA dehydrogenase, HADHA, HADH
User Note: Optimal dilutions for each application to be determined by the researcher.
BACKGROUND: This gene encodes the alpha subunit of the mitochondrial trifunctional protein, which catalyzes the last three steps of mitochondrial beta-oxidation of long chain fatty acids. The mitochondrial membrane-bound heterocomplex is composed of four alpha and four beta subunits, with the alpha subunit catalyzing the 3-hydroxyacyl-CoA dehydrogenase and enoyl-CoA hydratase activities. Mutations in this gene result in trifunctional protein deficiency or LCHAD deficiency. The genes of the alpha and beta subunits of the mitochondrial trifunctional protein are located adjacent to each other in the human genome in a head-to-head orientation.
![[KO Validated] HADHA Rabbit pAb](https://cdn11.bigcommerce.com/s-452hpg8iuh/images/stencil/500x659/products/396125/574598/unnamed-776x1024__91681.1646254488__92229.1646256048__22460.1646652158.png?c=2 "[KO Validated] HADHA Rabbit pAb")
