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Product Description
P2RY12 Antibody | 16-866 | ProSci
Host: Rabbit
Reactivity: Human, Mouse, Rat
Homology: N/A
Immunogen: A synthetic peptide corresponding to a sequence within amino acids 200 to the C-terminus of human P2RY12 (NP_795345.1) .
Research Area: Neuroscience, Signal Transduction
Tested Application: WB
Application: WB: 1:500 - 1:2000
Specificiy: N/A
Positive Control 1: U-251MG
Positive Control 2: HepG2
Positive Control 3: PC-12
Positive Control 4: DU145
Positive Control 5: Mouse brain
Positive Control 6: Rat testis
Molecular Weight: Observed: 50kDa
Validation: N/A
Isoform: N/A
Purification: Affinity purification
Clonality: Polyclonal
Clone: N/A
Isotype: IgG
Conjugate: Unconjugated
Physical State: Liquid
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Concentration: N/A
Storage Condition: Store at -20˚C. Avoid freeze / thaw cycles.
Alternate Name: ADPG-R, BDPLT8, HORK3, P2T (AC) , P2Y (12) R, P2Y (AC) , P2Y (ADP) , P2Y (cyc) , P2Y12, SP1999, P2Y purinoceptor 12, ADP-glucose receptor, G-protein coupled receptor SP1999, Gi-coupled ADP receptor HORK3, P2Y12 platelet ADP receptor, purinergic receptor P2RY12, purinergic receptor P2Y, G-protein coupled, 12, putative G-protein coupled receptor
User Note: Optimal dilutions for each application to be determined by the researcher.
BACKGROUND: The product of this gene belongs to the family of G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor is involved in platelet aggregation, and is a potential target for the treatment of thromboembolisms and other clotting disorders. Mutations in this gene are implicated in bleeding disorder, platelet type 8 (BDPLT8) . Alternative splicing results in multiple transcript variants of this gene.
