Product Description
PIP4K2A Antibody | 22-946 | ProSci
Host: Rabbit
Reactivity: Human, Mouse, Rat
Homology: N/A
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 120-350 of human PIP4K2A (NP_005019.2) .
Research Area: Cell Cycle, Signal Transduction
Tested Application: WB, IHC, IF
Application: WB: 1:500 - 1:2000
IHC: 1:50 - 1:200
IF: 1:50 - 1:200
Specificiy: N/A
Positive Control 1: Jurkat
Positive Control 2: MCF7
Positive Control 3: Mouse brain
Positive Control 4: Mouse spinal cord
Positive Control 5: Rat brain
Positive Control 6: N/A
Molecular Weight: Observed: 46kDa
Validation: N/A
Isoform: N/A
Purification: Affinity purification
Clonality: Polyclonal
Clone: N/A
Isotype: IgG
Conjugate: Unconjugated
Physical State: Liquid
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Concentration: N/A
Storage Condition: Store at -20˚C. Avoid freeze / thaw cycles.
Alternate Name: PIP4K2A, PI (5) P 4-kinase type II alpha, PIP5KII-alpha, PIP5KIII, PIPK, PtdIns (4) P-5-kinase B isoform, PtdIns (4) P-5-kinase C isoform, PI5P4KA, PIP4KII-alpha, PIP5K2, PIP5KIIalpha, PIP5K2A, PIP5KIIA
User Note: Optimal dilutions for each application to be determined by the researcher.
BACKGROUND: Phosphatidylinositol-5, 4-bisphosphate, the precursor to second messengers of the phosphoinositide signal transduction pathways, is thought to be involved in the regulation of secretion, cell proliferation, differentiation, and motility. The protein encoded by this gene is one of a family of enzymes capable of catalyzing the phosphorylation of phosphatidylinositol-5-phosphate on the fourth hydroxyl of the myo-inositol ring to form phosphatidylinositol-5, 4-bisphosphate. The amino acid sequence of this enzyme does not show homology to other kinases, but the recombinant protein does exhibit kinase activity. This gene is a member of the phosphatidylinositol-5-phosphate 4-kinase family.