Product Description
ROBO1 Antibody | 15-984 | ProSci
Host: Rabbit
Reactivity: Human, Mouse, Rat
Homology: N/A
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1452-1651 of human ROBO1 (NP_002932.1) .
Research Area: Cancer, Neuroscience
Tested Application: WB, IHC, IF
Application: WB: 1:200 - 1:2000
IHC: 1:50 - 1:200
IF: 1:50 - 1:200
Specificiy: N/A
Positive Control 1: 293T
Positive Control 2: U-251MG
Positive Control 3: HeLa
Positive Control 4: 293T
Positive Control 5: U-251MG
Positive Control 6: HeLa
Molecular Weight: Observed: 270kDa
Validation: N/A
Isoform: N/A
Purification: Affinity purification
Clonality: Polyclonal
Clone: N/A
Isotype: IgG
Conjugate: Unconjugated
Physical State: Liquid
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Concentration: N/A
Storage Condition: Store at -20˚C. Avoid freeze / thaw cycles.
Alternate Name: ROBO1, roundabout, axon guidance receptor, homolog 1 (Drosophila) , HGNC:10249, DUTT1, FLJ21882, SAX3, roundabout 1
User Note: Optimal dilutions for each application to be determined by the researcher.
BACKGROUND: Bilateral symmetric nervous systems have special midline structures that establish a partition between the two mirror image halves. Some axons project toward and across the midline in response to long-range chemoattractants emanating from the midline. The product of this gene is a member of the immunoglobulin gene superfamily and encodes an integral membrane protein that functions in axon guidance and neuronal precursor cell migration. This receptor is activated by SLIT-family proteins, resulting in a repulsive effect on glioma cell guidance in the developing brain. A related gene is located at an adjacent region on chromosome 3. Multiple transcript variants encoding different isoforms have been found for this gene.