Product Description
TMPRSS2 Antibody [ARC2373] | 24-034 | ProSci
Host: Rabbit
Reactivity: Virus
Homology: N/A
Immunogen: Synthetic Peptide
Research Area: Infectious Disease
Tested Application: WB, IHC
Application: WB: 1:500 - 1:2000, IHC: 1:50 - 1:200
Specificiy: N/A
Positive Control 1: N/A
Positive Control 2: N/A
Positive Control 3: N/A
Positive Control 4: N/A
Positive Control 5: N/A
Positive Control 6: N/A
Molecular Weight: N/A
Validation: N/A
Isoform: N/A
Purification: Affinity purification
Clonality: Monoclonal
Clone: ARC1439
Isotype: IgG
Conjugate: Unconjugated
Physical State: Liquid
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH 7.3
Concentration: N/A
Storage Condition: Store at 4˚C short term. Aliquot and store at -20˚C long term. Avoid freeze-thaw cycles.
Alternate Name: PP9284, PRSS10, transmembrane serine protease 2
User Note: Optimal dilutions for each application to be determined by the researcher.
BACKGROUND: This gene encodes a protein that belongs to the serine protease family. The encoded protein contains a type II transmembrane domain, a receptor class A domain, a scavenger receptor cysteine-rich domain and a protease domain. Serine proteases are known to be involved in many physiological and pathological processes. This gene was demonstrated to be up-regulated by androgenic hormones in prostate cancer cells and down-regulated in androgen-independent prostate cancer tissue. The protease domain of this protein is thought to be cleaved and secreted into cell media after autocleavage. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2008]