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Product Description
Cusatuzumab (CD70/TNFSF7) Antibody, Monoclonal | 10-877 | ProSci
Host: N/A
Reactivity: N/A
Homology: N/A
Immunogen: Humanized / CD70/TNFSF7 [Homo sapiens]
Research Area: Drug Analogues
Tested Application: N/A
Application: N/A
Specificiy: N/A
Positive Control 1: N/A
Positive Control 2: N/A
Positive Control 3: N/A
Positive Control 4: N/A
Positive Control 5: N/A
Positive Control 6: N/A
Molecular Weight: N/A
Validation: N/A
Isoform: N/A
Purification: >95%
Clonality: Monoclonal
Clone: N/A
Isotype: IgG1-lambda
Conjugate: Unconjugated
Physical State: N/A
Buffer: PBS buffer pH7.5
Concentration: N/A
Storage Condition: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8 ˚C for 1-2 weeks. Store at -20 ˚C for 12 months. Store at -80 ˚C for long term storage.
Alternate Name: ARGX-110
User Note: Optimal dilutions for each application to be determined by the researcher.
BACKGROUND: Cusatuzumab is SIMPLE antibody targeting CD70, which is an immune checkpoint target involving hematological malignancies, various solid tumors, and various autoimmune diseases. cusatuzumab aims to block CD70 by killing CD70-expressing cancer cells through complement-dependent cytotoxicity, enhancing antibody-dependent cell-mediated phagocytosis and enhancing antibody-dependent cell-mediated cytotoxicity Immunological monitoring of solid tumors.
