Product Description
CASP2 Antibody | 13-287 | ProSci
Host: Rabbit
Reactivity: Human, Mouse
Homology: N/A
Immunogen: A synthetic peptide of human CASP2
Research Area: Apoptosis, Cancer, Cell Cycle, Immunology, Signal Transduction
Tested Application: WB, IHC, Flow
Application: WB: 1:500 - 1:1000
IHC: 1:20 - 1:50
Flow: 1:20 - 1:50
Specificiy: N/A
Positive Control 1: Mouse kidney
Positive Control 2: N/A
Positive Control 3: N/A
Positive Control 4: N/A
Positive Control 5: N/A
Positive Control 6: N/A
Molecular Weight: Observed: 51kDa
Validation: N/A
Isoform: N/A
Purification: Affinity purification
Clonality: Polyclonal
Clone: N/A
Isotype: IgG
Conjugate: Unconjugated
Physical State: Liquid
Buffer: PBS with 0.02% sodium azide, pH7.3.
Concentration: N/A
Storage Condition: Store at 4˚C. Avoid freeze / thaw cycles.
Alternate Name: Caspase-2 Antibody: ICH1, NEDD2, CASP-2, NEDD-2, PPP1R57, ICH1, Caspase-2, Neural precursor cell expressed developmentally down-regulated protein 2
User Note: Optimal dilutions for each application to be determined by the researcher.
BACKGROUND: This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Caspases mediate cellular apoptosis through the proteolytic cleavage of specific protein substrates. The encoded protein may function in stress-induced cell death pathways, cell cycle maintenance, and the suppression of tumorigenesis. Increased expression of this gene may play a role in neurodegenerative disorders including Alzheimer's disease, Huntington's disease and temporal lobe epilepsy. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.