Product Description
DIDO1 Antibody | 22-235 | ProSci
Host: Rabbit
Reactivity: Human
Homology: N/A
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human DIDO1 (NP_071388.2) .
Research Area: Apoptosis, Cell Cycle
Tested Application: WB, IF
Application: WB: 1:500 - 1:2000
IF: 1:20 - 1:50
Specificiy: N/A
Positive Control 1: HT-29
Positive Control 2: MCF7
Positive Control 3: HepG2
Positive Control 4: BT-474
Positive Control 5: N/A
Positive Control 6: N/A
Molecular Weight: Observed: 76kDa/244kDa
Validation: N/A
Isoform: N/A
Purification: Affinity purification
Clonality: Polyclonal
Clone: N/A
Isotype: IgG
Conjugate: Unconjugated
Physical State: Liquid
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Concentration: N/A
Storage Condition: Store at -20˚C. Avoid freeze / thaw cycles.
Alternate Name: DIDO1, BYE1, DIO1, DATF1, DIDO2, DIDO3, DIO-1, DATF-1, C20orf158, dJ885L7.8
User Note: Optimal dilutions for each application to be determined by the researcher.
BACKGROUND: Apoptosis, a major form of cell death, is an efficient mechanism for eliminating unwanted cells and is of central importance for development and homeostasis in metazoan animals. In mice, the death inducer-obliterator-1 gene is upregulated by apoptotic signals and encodes a cytoplasmic protein that translocates to the nucleus upon apoptotic signal activation. When overexpressed, the mouse protein induced apoptosis in cell lines growing in vitro. This gene is similar to the mouse gene and therefore is thought to be involved in apoptosis. Alternatively spliced transcripts have been found for this gene, encoding multiple isoforms.