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Product Description
HDAC1 Antibody, KO Validated | 13-098 | ProSci
Host: Rabbit
Reactivity: Human, Mouse, Rat
Homology: N/A
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 393-482 of human HDAC1 (NP_004955.2) .
Research Area: Apoptosis, Cell Cycle, Immunology, Neuroscience, Signal Transduction, Stem Cell
Tested Application: WB, IHC, IF, IP
Application: WB: 1:500 - 1:2000
IHC: 1:100 - 1:200
IF: 1:50 - 1:100
IP: 1:50 - 1:100
Specificiy: N/A
Positive Control 1: 293T
Positive Control 2: HeLa
Positive Control 3: HepG2
Positive Control 4: MCF7
Positive Control 5: Mouse thymus
Positive Control 6: Mouse testis
Molecular Weight: Observed: 62kDa
Validation: Antibody is Knockout validated.
Isoform: N/A
Purification: Affinity purification
Clonality: Polyclonal
Clone: N/A
Isotype: IgG
Conjugate: Unconjugated
Physical State: Liquid
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Concentration: N/A
Storage Condition: Store at -20˚C. Avoid freeze / thaw cycles.
Alternate Name: HDAC1 Antibody: HD1, RPD3, GON-10, RPD3L1, Histone deacetylase 1, HD1
User Note: Optimal dilutions for each application to be determined by the researcher.
BACKGROUND: Histone acetylation and deacetylation, catalyzed by multisubunit complexes, play a key role in the regulation of eukaryotic gene expression. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family and is a component of the histone deacetylase complex. It also interacts with retinoblastoma tumor-suppressor protein and this complex is a key element in the control of cell proliferation and differentiation. Together with metastasis-associated protein-2, it deacetylates p53 and modulates its effect on cell growth and apoptosis.
![[KO Validated] HDAC1 Rabbit mAb](https://cdn11.bigcommerce.com/s-452hpg8iuh/images/stencil/500x659/products/396128/574601/unnamed-776x1024__91681.1646254488__92229.1646256048__49126.1646652159.png?c=2 "[KO Validated] HDAC1 Rabbit mAb")
