Product Description
MSH2 Antibody | 13-955 | ProSci
Host: Rabbit
Reactivity: Human, Mouse, Rat
Homology: N/A
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human MSH2 (NP_000242.1) .
Research Area: Apoptosis, Cancer, Cell Cycle
Tested Application: WB, IP
Application: WB: 1:500 - 1:2000
IP: 1:20 - 1:50
Specificiy: N/A
Positive Control 1: NIH/3T3
Positive Control 2: A431
Positive Control 3: A549
Positive Control 4: Mouse testis
Positive Control 5: Mouse thymus
Positive Control 6: Mouse brain
Molecular Weight: Observed: 105kDa
Validation: N/A
Isoform: N/A
Purification: Affinity purification
Clonality: Polyclonal
Clone: N/A
Isotype: IgG
Conjugate: Unconjugated
Physical State: Liquid
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Concentration: N/A
Storage Condition: Store at -20˚C. Avoid freeze / thaw cycles.
Alternate Name: MSH2, FCC1, COCA1, HNPCC, LCFS2, HNPCC1
User Note: Optimal dilutions for each application to be determined by the researcher.
BACKGROUND: This locus is frequently mutated in hereditary nonpolyposis colon cancer (HNPCC) . When cloned, it was discovered to be a human homolog of the E. coli mismatch repair gene mutS, consistent with the characteristic alterations in microsatellite sequences (RER+ phenotype) found in HNPCC. Two transcript variants encoding different isoforms have been found for this gene.