Product Description
PARP3 Antibody | 27-941 | ProSci
Host: Rabbit
Reactivity: Human
Homology: N/A
Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human PARP3.
Research Area: Apoptosis
Tested Application: E, WB, IHC
Application: PARP3 antibody can be used for detection of PARP3 by ELISA at 1:62500. PARP3 antibody can be used for detection of PARP3 by western blot at 1.0-2.0 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50, 000 - 100, 000.
Specificiy: N/A
Positive Control 1: Cat. No. 1211 - HepG2 Cell Lysate
Positive Control 2: N/A
Positive Control 3: N/A
Positive Control 4: N/A
Positive Control 5: N/A
Positive Control 6: N/A
Molecular Weight: 59 kDa, 61 kDa, 60 kDa
Validation: N/A
Isoform: N/A
Purification: Antibody is purified by peptide affinity chromatography method.
Clonality: Polyclonal
Clone: N/A
Isotype: N/A
Conjugate: Unconjugated
Physical State: Liquid
Buffer: Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Concentration: batch dependent
Storage Condition: For short periods of storage (days) store at 4˚C. For longer periods of storage, store PARP3 antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.
Alternate Name: PARP3, IRT1, ARTD3, ADPRT3, ADPRTL2, ADPRTL3, PADPRT-3
User Note: Optimal dilutions for each application to be determined by the researcher.
BACKGROUND: PARP3 belongs to the PARP family. These enzymes modify nuclear proteins by poly-ADP-ribosylation, which is required for DNA repair, regulation of apoptosis, and maintenance of genomic stability. PARP3 is preferentially localized to the daughter centriole throughout the cell cycle. Alternatively spliced transcript variants encoding different isoforms have been identified.