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Product Description
RASSF5 Antibody | 22-908 | ProSci
Host: Rabbit
Reactivity: Human, Mouse, Rat
Homology: N/A
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-265 of human RASSF5 (NP_872606.1) .
Research Area: Apoptosis, Cancer, Cell Cycle, Immunology, Signal Transduction
Tested Application: WB, IHC
Application: WB: 1:500 - 1:2000
IHC: 1:50 - 1:200
Specificiy: N/A
Positive Control 1: THP-1
Positive Control 2: A-549
Positive Control 3: 293T
Positive Control 4: Jurkat
Positive Control 5: Mouse brain
Positive Control 6: Mouse liver
Molecular Weight: Observed: 37kDa, 45kDa
Validation: N/A
Isoform: N/A
Purification: Affinity purification
Clonality: Polyclonal
Clone: N/A
Isotype: IgG
Conjugate: Unconjugated
Physical State: Liquid
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Concentration: N/A
Storage Condition: Store at -20˚C. Avoid freeze / thaw cycles.
Alternate Name: NORE1, RAPL, Ras association domain-containing protein 5, New ras effector 1, Maxp1, NORE1A, NORE1B, RASSF3
User Note: Optimal dilutions for each application to be determined by the researcher.
BACKGROUND: This gene is a member of the Ras association domain family. It functions as a tumor suppressor, and is inactivated in a variety of cancers. The encoded protein localizes to centrosomes and microtubules, and associates with the GTP-activated forms of Ras, Rap1, and several other Ras-like small GTPases. The protein regulates lymphocyte adhesion and suppresses cell growth in response to activated Rap1 or Ras. Multiple transcript variants encoding different isoforms have been found for this gene.
