Product Description
SFRP1 Antibody | 18-866 | ProSci
Host: Rabbit
Reactivity: Human, Mouse, Rat
Homology: N/A
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 30-314 of human SFRP1 (NP_003003.3) .
Research Area: Apoptosis, Cell Cycle, Neuroscience, Stem Cell
Tested Application: WB, IHC
Application: WB: 1:100 - 1:500
IHC: 1:50 - 1:100
Specificiy: N/A
Positive Control 1: NCI-H460
Positive Control 2: 293T
Positive Control 3: SKOV3
Positive Control 4: Mouse kidney
Positive Control 5: N/A
Positive Control 6: N/A
Molecular Weight: Observed: 35kDa
Validation: N/A
Isoform: N/A
Purification: Affinity purification
Clonality: Polyclonal
Clone: N/A
Isotype: IgG
Conjugate: Unconjugated
Physical State: Liquid
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Concentration: N/A
Storage Condition: Store at -20˚C. Avoid freeze / thaw cycles.
Alternate Name: SFRP1, FRP, FRP1, FrzA, FRP-1, SARP2
User Note: Optimal dilutions for each application to be determined by the researcher.
BACKGROUND: This gene encodes a member of the SFRP family that contains a cysteine-rich domain homologous to the putative Wnt-binding site of Frizzled proteins. Members of this family act as soluble modulators of Wnt signaling; epigenetic silencing of SFRP genes leads to deregulated activation of the Wnt-pathway which is associated with cancer. This gene may also be involved in determining the polarity of photoreceptor cells in the retina.