Product Description
UBC Antibody | 18-994 | ProSci
Host: Rabbit
Reactivity: Human, Mouse, Rat
Homology: N/A
Immunogen: A synthetic peptide corresponding to a sequence within amino acids 1-100 of human UBC (NP_066289.3) .
Research Area: Apoptosis, Cell Cycle
Tested Application: WB, IHC, IF
Application: WB: 1:1000 - 1:2000
IHC: 1:50 - 1:100
IF: 1:50 - 1:100
Specificiy: N/A
Positive Control 1: 293T
Positive Control 2: BT-474
Positive Control 3: HepG2
Positive Control 4: U-251MG
Positive Control 5: A-549
Positive Control 6: Mouse testis
Molecular Weight: Observed: 12kD/25kDa
Validation: N/A
Isoform: N/A
Purification: Affinity purification
Clonality: Polyclonal
Clone: N/A
Isotype: IgG
Conjugate: Unconjugated
Physical State: Liquid
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Concentration: N/A
Storage Condition: Store at -20˚C. Avoid freeze / thaw cycles.
Alternate Name: Polyubiquitin-C, Ubiquitin, UBC
User Note: Optimal dilutions for each application to be determined by the researcher.
BACKGROUND: This gene represents a ubiquitin gene, ubiquitin C. The encoded protein is a polyubiquitin precursor. Conjugation of ubiquitin monomers or polymers can lead to various effects within a cell, depending on the residues to which ubiquitin is conjugated. Ubiquitination has been associated with protein degradation, DNA repair, cell cycle regulation, kinase modification, endocytosis, and regulation of other cell signaling pathways.