Product Description
UNC5B Antibody | 15-814 | ProSci
Host: Rabbit
Reactivity: Human, Mouse, Rat
Homology: N/A
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 290-377 of human UNC5B (NP_734465.2) .
Research Area: Apoptosis, Cell Cycle, Neuroscience, Signal Transduction
Tested Application: WB, IF
Application: WB: 1:500 - 1:2000
IF: 1:50 - 1:100
Specificiy: N/A
Positive Control 1: U-87MG
Positive Control 2: A-549
Positive Control 3: 293T
Positive Control 4: Mouse brain
Positive Control 5: Mouse lung
Positive Control 6: Mouse kidney
Molecular Weight: Observed: 104kDa
Validation: N/A
Isoform: N/A
Purification: Affinity purification
Clonality: Polyclonal
Clone: N/A
Isotype: IgG
Conjugate: Unconjugated
Physical State: Liquid
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Concentration: N/A
Storage Condition: Store at -20˚C. Avoid freeze / thaw cycles.
Alternate Name: 6330415E02Rik, A630020F16, D10Bwg0792e, netrin receptor UNC5B, protein unc-5 homolog 2, protein unc-5 homolog B, unc5 homolog 2, unc-5 homolog 2, unc-5 homolog B (C. elegans) , Unc5b, Unc5h2, P53RDL1, UNC5H2, UNQ1883/PRO4326
User Note: Optimal dilutions for each application to be determined by the researcher.
BACKGROUND: This gene encodes a member of the netrin family of receptors. This particular protein mediates the repulsive effect of netrin-1 and is a vascular netrin receptor. This encoded protein is also in a group of proteins called dependence receptors (DpRs) which are involved in pro- and anti-apoptotic processes. Many DpRs are involved in embryogenesis and in cancer progression. Two alternatively spliced transcript variants have been described for this gene.