Product Description
USH1C Antibody | 19-353 | ProSci
Host: Rabbit
Reactivity: Human, Mouse, Rat
Homology: N/A
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-100 of zebrafish USH1C (NP_001035018.1) .
Research Area: Apoptosis, Cell Cycle, Neuroscience
Tested Application: WB, IHC
Application: WB: 1:200 - 1:2000
IHC: 1:50 - 1:200
Specificiy: N/A
Positive Control 1: HT-29
Positive Control 2: Mouse kidney
Positive Control 3: Mouse small intestine
Positive Control 4: Rat testis
Positive Control 5: Rat kidney
Positive Control 6: N/A
Molecular Weight: Observed: 73kDa
Validation: N/A
Isoform: N/A
Purification: Affinity purification
Clonality: Polyclonal
Clone: N/A
Isotype: IgG
Conjugate: Unconjugated
Physical State: Liquid
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Concentration: N/A
Storage Condition: Store at -20˚C. Avoid freeze / thaw cycles.
Alternate Name: zgc:136806, harmonin, Usher syndrome 1C (autosomal recessive, severe) , harmonin pseudogene
User Note: Optimal dilutions for each application to be determined by the researcher.
BACKGROUND: This gene encodes a scaffold protein that functions in the assembly of Usher protein complexes. The protein contains PDZ domains, a coiled-coil region with a bipartite nuclear localization signal and a PEST degradation sequence. Defects in this gene are the cause of Usher syndrome type 1C and non-syndromic sensorineural deafness autosomal recessive type 18. Multiple transcript variants encoding different isoforms have been found for this gene.