Product Description
BCL2 Antibody | 13-890 | ProSci
Host: Rabbit
Reactivity: Human, Mouse, Rat
Homology: N/A
Immunogen: A synthetic peptide corresponding to a sequence within amino acids 1-100 of human BCL2 (NP_000624.2) .
Research Area: Apoptosis, Autophagy, Cancer, Cell Cycle, Immunology, Neuroscience, Signal Transduction, Stem Cell
Tested Application: WB, IHC, IP
Application: WB: 1:500 - 1:2000
IHC: 1:50 - 1:200
IP: 1:50 - 1:100
Specificiy: N/A
Positive Control 1: HL-60
Positive Control 2: Jurkat
Positive Control 3: HeLa
Positive Control 4: Mouse lung
Positive Control 5: Mouse testis
Positive Control 6: Rat liver
Molecular Weight: Observed: 28kDa
Validation: N/A
Isoform: N/A
Purification: Affinity purification
Clonality: Polyclonal
Clone: N/A
Isotype: IgG
Conjugate: Unconjugated
Physical State: Liquid
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Concentration: N/A
Storage Condition: Store at -20˚C. Avoid freeze / thaw cycles.
Alternate Name: Bcl-2 Antibody: Bcl-2, PPP1R50, Apoptosis regulator Bcl-2
User Note: Optimal dilutions for each application to be determined by the researcher.
BACKGROUND: This gene encodes an integral outer mitochondrial membrane protein that blocks the apoptotic death of some cells such as lymphocytes. Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma. Alternative splicing results in multiple transcript variants.