Product Description
Mitofusin 2 Antibody | 19-833 | ProSci
Host: Rabbit
Reactivity: Human, Mouse, Rat
Homology: N/A
Immunogen: Recombinant protein of human Mitofusin 2
Research Area: Apoptosis, Autophagy, Cancer, Cell Cycle, Neuroscience, Signal Transduction
Tested Application: WB, IHC, IP
Application: WB: 1:1000 - 1:4000
IHC: 1:50 - 1:200
IP: 1:20 - 1:50
Specificiy: N/A
Positive Control 1: LO2
Positive Control 2: U-87MG
Positive Control 3: 293T
Positive Control 4: SW480
Positive Control 5: Mouse kidney
Positive Control 6: Mouse liver
Molecular Weight: Observed: 86kDa
Validation: N/A
Isoform: N/A
Purification: Affinity purification
Clonality: Polyclonal
Clone: N/A
Isotype: IgG
Conjugate: Unconjugated
Physical State: Liquid
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Concentration: N/A
Storage Condition: Store at -20˚C. Avoid freeze / thaw cycles.
Alternate Name: MFN2 Antibody: HSG, MARF, CMT2A, CPRP1, CMT2A2, KIAA0214, Mitofusin-2, Transmembrane GTPase MFN2
User Note: Optimal dilutions for each application to be determined by the researcher.
BACKGROUND: This gene encodes a mitochondrial membrane protein that participates in mitochondrial fusion and contributes to the maintenance and operation of the mitochondrial network. This protein is involved in the regulation of vascular smooth muscle cell proliferation, and it may play a role in the pathophysiology of obesity. Mutations in this gene cause Charcot-Marie-Tooth disease type 2A2, and hereditary motor and sensory neuropathy VI, which are both disorders of the peripheral nervous system. Defects in this gene have also been associated with early-onset stroke. Two transcript variants encoding the same protein have been identified.