Product Description
B4GALT7 Antibody | 19-396 | ProSci
Host: Rabbit
Reactivity: Human, Mouse
Homology: N/A
Immunogen: A synthetic Peptide of human B4GALT7
Research Area: Cancer, Cell Cycle, Signal Transduction
Tested Application: WB
Application: WB: 1:500 - 1:1000
Specificiy: N/A
Positive Control 1: Human pancreas
Positive Control 2: N/A
Positive Control 3: N/A
Positive Control 4: N/A
Positive Control 5: N/A
Positive Control 6: N/A
Molecular Weight: Observed: 37kDa
Validation: N/A
Isoform: N/A
Purification: Affinity purification
Clonality: Polyclonal
Clone: N/A
Isotype: IgG
Conjugate: Unconjugated
Physical State: Liquid
Buffer: PBS with 0.02% sodium azide, pH7.3.
Concentration: N/A
Storage Condition: Store at 4˚C. Avoid freeze / thaw cycles.
Alternate Name: EDSP1, EDSSLA, EDSSPD1, XGALT1, XGPT, XGPT1, beta-1, 4-galactosyltransferase 7, UDP-Gal:beta-GlcNAc beta-1, 4-galactosyltransferase 7, UDP-galactose:beta-N-acetylglucosamine beta-1, 4-galactosyltransferase 7, UDP-galactose:beta-xylose beta-1, 4-galactosyltransferase, beta-1, 4-GalTase 7, beta-1, 4-galactosyltransferase VII, beta4Gal-T7, beta4GalT-VII, galactosyltransferase I, proteoglycan UDP-galactose:beta-xylose beta1, 4-galactosyltransferase I, xylosylprotein 4-beta-galactosyltransferase, xylosylprotein beta 1, 4-galactosyltransferase, polypeptide 7, xylosylprotein beta-1, 4-galactosyltransferase
User Note: Optimal dilutions for each application to be determined by the researcher.
BACKGROUND: This gene is a member of the beta-1, 4-galactosyltransferase (beta4GalT) family. Family members encode type II membrane-bound glycoproteins that appear to have exclusive specificity for the donor substrate UDP-galactose. Each beta4GalT member has a distinct function in the biosynthesis of different glycoconjugates and saccharide structures. As type II membrane proteins, they have an N-terminal hydrophobic signal sequence that directs the protein to the Golgi apparatus which then remains uncleaved to function as a transmembrane anchor. The enzyme encoded by this gene attaches the first galactose in the common carbohydrate-protein linkage (GlcA-beta1, 3-Gal-beta1, 3-Gal-beta1, 4-Xyl-beta1-O-Ser) found in proteoglycans. This enzyme differs from other beta4GalTs because it lacks the conserved Cys residues found in beta4GalT1-beta4GalT6 and it is located in cis-Golgi instead of trans-Golgi. Mutations in this gene have been associated with the progeroid form of Ehlers-Danlos syndrome.