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Product Description
POR Antibody, KO Validated | 23-429 | ProSci
Host: Rabbit
Reactivity: Human, Mouse, Rat
Homology: N/A
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-250 of human POR (NP_000932.3) .
Research Area: Cancer, Signal Transduction
Tested Application: WB, IHC, IF
Application: WB: 1:500 - 1:2000
IHC: 1:50 - 1:100
IF: 1:50 - 1:200
Specificiy: N/A
Positive Control 1: A-549
Positive Control 2: HeLa
Positive Control 3: MCF-7
Positive Control 4: 293T
Positive Control 5: Mouse liver
Positive Control 6: Mouse skin
Molecular Weight: Observed: 77kDa
Validation: Antibody is Knockout validated.
Isoform: N/A
Purification: Affinity purification
Clonality: Polyclonal
Clone: N/A
Isotype: IgG
Conjugate: Unconjugated
Physical State: Liquid
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Concentration: N/A
Storage Condition: Store at -20˚C. Avoid freeze / thaw cycles.
Alternate Name: POR, CPR, CYPOR, DKFZp686G04235, FLJ26468, P450R
User Note: Optimal dilutions for each application to be determined by the researcher.
BACKGROUND: This gene encodes an endoplasmic reticulum membrane oxidoreductase with an FAD-binding domain and a flavodoxin-like domain. The protein binds two cofactors, FAD and FMN, which allow it to donate electrons directly from NADPH to all microsomal P450 enzymes. Mutations in this gene have been associated with various diseases, including apparent combined P450C17 and P450C21 deficiency, amenorrhea and disordered steroidogenesis, congenital adrenal hyperplasia and Antley-Bixler syndrome.
![[KO Validated] POR Polyclonal Antibody](https://cdn11.bigcommerce.com/s-452hpg8iuh/images/stencil/500x659/products/295474/455611/sab-signalway-antibody__92073.1641690747__85634.1641691412.gif?c=2 "[KO Validated] POR Polyclonal Antibody")
