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Product Description
CDSN Antibody | 15-624 | ProSci
Host: Rabbit
Reactivity: Human, Mouse, Rat
Homology: N/A
Immunogen: A synthetic peptide corresponding to a sequence within amino acids 100-200 of human CDSN (NP_001255.3) .
Research Area: Cell Cycle, Signal Transduction
Tested Application: WB
Application: WB: 1:500 - 1:2000
Specificiy: N/A
Positive Control 1: BxPC-3
Positive Control 2: A-431
Positive Control 3: NIH/3T3
Positive Control 4: Mouse skin
Positive Control 5: Mouse skeletal muscle
Positive Control 6: Rat skin
Molecular Weight: Observed: 52kDa
Validation: N/A
Isoform: N/A
Purification: Affinity purification
Clonality: Polyclonal
Clone: N/A
Isotype: IgG
Conjugate: Unconjugated
Physical State: Liquid
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Concentration: N/A
Storage Condition: Store at -20˚C. Avoid freeze / thaw cycles.
Alternate Name: CDSN, corneodesmosin, D6S586E, HTSS, S, differentiated keratinocyte S protein
User Note: Optimal dilutions for each application to be determined by the researcher.
BACKGROUND: This gene encodes a protein found in corneodesmosomes, which localize to human epidermis and other cornified squamous epithelia. The encoded protein undergoes a series of cleavages during corneocyte maturation. This gene is highly polymorphic in human populations, and variation has been associated with skin diseases such as psoriasis, hypotrichosis and peeling skin syndrome. The gene is located in the major histocompatibility complex (MHC) class I region on chromosome 6.
