Product Description
CSNK2B Antibody | 18-840 | ProSci
Host: Rabbit
Reactivity: Human, Mouse, Rat
Homology: N/A
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-215 of human CSNK2B (NP_001311.3) .
Research Area: Cell Cycle, Signal Transduction, Stem Cell
Tested Application: WB, IHC
Application: WB: 1:500 - 1:2000
IHC: 1:50 - 1:200
Specificiy: N/A
Positive Control 1: U-87MG
Positive Control 2: HeLa
Positive Control 3: SW620
Positive Control 4: MCF7
Positive Control 5: Mouse spleen
Positive Control 6: Mouse kidney
Molecular Weight: Observed: 25kDa
Validation: N/A
Isoform: N/A
Purification: Affinity purification
Clonality: Polyclonal
Clone: N/A
Isotype: IgG
Conjugate: Unconjugated
Physical State: Liquid
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Concentration: N/A
Storage Condition: Store at -20˚C. Avoid freeze / thaw cycles.
Alternate Name: CSNK2B, casein kinase 2, beta polypeptide, CK2B, CK2N, CSK2B, G5A, CK II beta, Casein kinase II beta subunit, alternative name: G5a, phosvitin, casein kinase II subunit beta, phosvitin, protein G5a
User Note: Optimal dilutions for each application to be determined by the researcher.
BACKGROUND: This gene encodes the beta subunit of casein kinase II, a ubiquitous protein kinase which regulates metabolic pathways, signal transduction, transcription, translation, and replication. The enzyme is composed of three subunits, alpha, alpha prime and beta, which form a tetrameric holoenzyme. The alpha and alpha prime subunits are catalytic, while the beta subunit serves regulatory functions. The enzyme localizes to the endoplasmic reticulum and the Golgi apparatus. Two transcript variants encoding different isoforms have been found for this gene.