Euro
USD
British Pound
NULL
Product Description
FSCN1 Antibody, KO Validated | 18-373 | ProSci
Host: Rabbit
Reactivity: Human, Mouse, Rat
Homology: N/A
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 394-493 of human FSCN1 (NP_003079.1) .
Research Area: Cell Cycle, Signal Transduction
Tested Application: WB, IHC, IF
Application: WB: 1:500 - 1:2000
IHC: 1:50 - 1:200
IF: 1:50 - 1:200
Specificiy: N/A
Positive Control 1: U-251MG
Positive Control 2: HeLa
Positive Control 3: NCI-H460
Positive Control 4: HepG2
Positive Control 5: SH-SY5Y
Positive Control 6: Mouse brain
Molecular Weight: Observed: 50kDa, 55kDa
Validation: Antibody is Knockout validated.
Isoform: N/A
Purification: Affinity purification
Clonality: Polyclonal
Clone: N/A
Isotype: IgG
Conjugate: Unconjugated
Physical State: Liquid
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Concentration: N/A
Storage Condition: Store at -20˚C. Avoid freeze / thaw cycles.
Alternate Name: Fascin, 55 kDa actin-bundling protein, Singed-like protein, p55, FSCN1, FAN1, HSN, SNL
User Note: Optimal dilutions for each application to be determined by the researcher.
BACKGROUND: This gene encodes a member of the fascin family of actin-binding proteins. Fascin proteins organize F-actin into parallel bundles, and are required for the formation of actin-based cellular protrusions. The encoded protein plays a critical role in cell migration, motility, adhesion and cellular interactions. Expression of this gene is known to be regulated by several microRNAs, and overexpression of this gene may play a role in the metastasis of multiple types of cancer by increasing cell motility. Expression of this gene is also a marker for Reed-Sternberg cells in Hodgkin's lymphoma. A pseudogene of this gene is located on the long arm of chromosome 15.
![[KO Validated] FSCN1 Polyclonal Antibody](https://cdn11.bigcommerce.com/s-452hpg8iuh/images/stencil/500x659/products/295413/455550/sab-signalway-antibody__92073.1641690747__52584.1641691394.gif?c=2 "[KO Validated] FSCN1 Polyclonal Antibody")
![[KO Validated] Fascin/FSCN1 Rabbit pAb](https://cdn11.bigcommerce.com/s-452hpg8iuh/images/stencil/500x659/products/396089/574562/unnamed-776x1024__91681.1646254488__92229.1646256048__21117.1646652141.png?c=2 "[KO Validated] Fascin/FSCN1 Rabbit pAb")
