Product Description
ME3 Antibody | 16-233 | ProSci
Host: Rabbit
Reactivity: Human, Mouse, Rat
Homology: N/A
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 505-604 of human ME3 (NP_001014811.1) .
Research Area: Cancer, Cell Cycle, Signal Transduction
Tested Application: WB
Application: WB: 1:500 - 1:2000
Specificiy: N/A
Positive Control 1: HT-29
Positive Control 2: 293T
Positive Control 3: Mouse brain
Positive Control 4: Mouse heart
Positive Control 5: Mouse kidney
Positive Control 6: Rat brain
Molecular Weight: Observed: 78kDa
Validation: N/A
Isoform: N/A
Purification: Affinity purification
Clonality: Polyclonal
Clone: N/A
Isotype: IgG
Conjugate: Unconjugated
Physical State: Liquid
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Concentration: N/A
Storage Condition: Store at -20˚C. Avoid freeze / thaw cycles.
Alternate Name: NADP-ME, NADP-dependent malic enzyme, mitochondrial, malate dehydrogenase (oxaloacetate-decarboxylating) (NADP (+) ) , malic enzyme 3, NADP (+) -dependent, mitochondrial, malic enzyme, NADP+-dependent, mitochondrial, mitochondrial NADP (+) -dependent malic enzyme 3, pyruvic-malic carboxylase
User Note: Optimal dilutions for each application to be determined by the researcher.
BACKGROUND: Malic enzyme catalyzes the oxidative decarboxylation of malate to pyruvate using either NAD+ or NADP+ as a cofactor. Mammalian tissues contain 3 distinct isoforms of malic enzyme: a cytosolic NADP (+) -dependent isoform, a mitochondrial NADP (+) -dependent isoform, and a mitochondrial NAD (+) -dependent isoform. This gene encodes a mitochondrial NADP (+) -dependent isoform. Multiple alternatively spliced transcript variants have been found for this gene, but the biological validity of some variants has not been determined.