Product Description
NDC80 Antibody | 15-371 | ProSci
Host: Rabbit
Reactivity: Human, Mouse, Rat
Homology: N/A
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 343-642 of human NDC80 (NP_006092.1) .
Research Area: Cancer, Cell Cycle
Tested Application: WB
Application: WB: 1:500 - 1:2000
Specificiy: N/A
Positive Control 1: K-562
Positive Control 2: Lovo
Positive Control 3: MCF7
Positive Control 4: 22Rv1
Positive Control 5: THP-1
Positive Control 6: 293T
Molecular Weight: Observed: 74kDa
Validation: N/A
Isoform: N/A
Purification: Affinity purification
Clonality: Polyclonal
Clone: N/A
Isotype: IgG
Conjugate: Unconjugated
Physical State: Liquid
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Concentration: N/A
Storage Condition: Store at -20˚C. Avoid freeze / thaw cycles.
Alternate Name: HEC, highly expressed in cancer, rich in leucine heptad repeats, HEC1, HEC-1, HEC, KNTC2
User Note: Optimal dilutions for each application to be determined by the researcher.
BACKGROUND: This gene encodes a component of the NDC80 kinetochore complex. The encoded protein consists of an N-terminal microtubule binding domain and a C-terminal coiled-coiled domain that interacts with other components of the complex. This protein functions to organize and stabilize microtubule-kinetochore interactions and is required for proper chromosome segregation.