Product Description
RBBP7 Antibody | 22-594 | ProSci
Host: Rabbit
Reactivity: Human, Mouse, Rat
Homology: N/A
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-230 of human RBBP7 (NP_002884.1) .
Research Area: Cell Cycle
Tested Application: WB, IF, IP, ChIP
Application: WB: 1:500 - 1:2000
IF: 1:50 - 1:100
IP: 1:50 - 1:200
ChIP: 1:50 - 1:200
Specificiy: N/A
Positive Control 1: SW480
Positive Control 2: HT-29
Positive Control 3: MCF-7
Positive Control 4: 293T
Positive Control 5: Mouse spleen
Positive Control 6: Mouse ovary
Molecular Weight: Observed: 48kDa
Validation: N/A
Isoform: N/A
Purification: Affinity purification
Clonality: Polyclonal
Clone: N/A
Isotype: IgG
Conjugate: Unconjugated
Physical State: Liquid
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Concentration: N/A
Storage Condition: Store at -20˚C. Avoid freeze / thaw cycles.
Alternate Name: Histone-binding protein RBBP7, Histone acetyltransferase type B subunit 2, Nucleosome-remodeling factor subunit RBAP46, Retinoblastoma-binding protein 7, RBBP-7, Retinoblastoma-binding protein p46, RBBP7, RBAP46
User Note: Optimal dilutions for each application to be determined by the researcher.
BACKGROUND: This protein is a ubiquitously expressed nuclear protein and belongs to a highly conserved subfamily of WD-repeat proteins. It is found among several proteins that binds directly to retinoblastoma protein, which regulates cell proliferation. The encoded protein is found in many histone deacetylase complexes, including mSin3 co-repressor complex. It is also present in protein complexes involved in chromatin assembly. This protein can interact with BRCA1 tumor-suppressor gene and may have a role in the regulation of cell proliferation and differentiation. Two transcript variants encoding different isoforms have been found for this gene.