Product Description
KIT Antibody | XW-7748 | ProSci
Host: Chicken
Reactivity: Human
Homology: N/A
Immunogen: 113-208
Research Area: Other
Tested Application: WB
Application: Mast/stem cell growth factor receptor antibody can be used for the detection of Mast/stem cell growth factor receptor by Western Blot.
Specificiy: N/A
Positive Control 1: N/A
Positive Control 2: N/A
Positive Control 3: N/A
Positive Control 4: N/A
Positive Control 5: N/A
Positive Control 6: N/A
Molecular Weight: 109.9 kDa (calculated)
Validation: N/A
Isoform: N/A
Purification: Immunoaffinity Purified
Clonality: Polyclonal
Clone: N/A
Isotype: N/A
Conjugate: Unconjugated
Physical State: Liquid
Buffer: Phosphate-Buffered Saline. No preservatives added.
Concentration: 1 mg/mL
Storage Condition: KIT antibody can be stored at 4˚C for short term (weeks) . Long term storage should be at -20˚C. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Alternate Name: SCFRPiebald trait protein, SCFR, PBT, C-Kit, CD117, Mast/stem cell growth factor receptor, Proto-oncogene tyrosine-protein kinase Kit, c-kit, CD117 antigen
User Note: Optimal dilutions for each application to be determined by the researcher.
BACKGROUND: FUNCTION: This is the receptor for stem cell factor (mast cell growth factor) . It has a tyrosine-protein kinase activity. Binding of the ligands leads to the autophosphorylation of KIT and its association with substrates such as phosphatidylinositol 3-kinase (Pi3K) .
DISEASE: Defects in KIT are a cause of gastrointestinal stromal tumor (GIST) [MIM:606764].
CATALYTIC ACTIVITY: ATP + a protein tyrosine = ADP + a protein tyrosine phosphate.