Product Description
PTPRJ Antibody | XW-7820 | ProSci
Host: Chicken
Reactivity: Human
Homology: N/A
Immunogen: 206-292
Research Area: Other
Tested Application: WB
Application: Protein-tyrosine phosphatase antibody can be used for the detection of Protein-tyrosine phosphatase by Western Blot.
Specificiy: N/A
Positive Control 1: N/A
Positive Control 2: N/A
Positive Control 3: N/A
Positive Control 4: N/A
Positive Control 5: N/A
Positive Control 6: N/A
Molecular Weight: 14.3 kDa (calculated)
Validation: N/A
Isoform: N/A
Purification: Immunoaffinity Purified
Clonality: Polyclonal
Clone: N/A
Isotype: N/A
Conjugate: Unconjugated
Physical State: Liquid
Buffer: Phosphate-Buffered Saline. No preservatives added.
Concentration: 1 mg/mL
Storage Condition: PTPRJ antibody can be stored at 4˚C for short term (weeks) . Long term storage should be at -20˚C. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Alternate Name: DEP1, Receptor-type tyrosine-protein phosphatase eta, Density-enhanced phosphatase 1, Protein-tyrosine phosphatase eta, DEP1, SCC1, CD148, HPTPeta, R-PTP-ETA, Proteintyrosine phosphatase
User Note: Optimal dilutions for each application to be determined by the researcher.
BACKGROUND: The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region containing five fibronectin type III repeats, a single transmembrane region, and a single intracytoplasmic catalytic domain, and thus represents a receptor-type PTP. This PTP is present in all hematopoietic lineages, and was shown to negatively regulate T cell receptor signaling possibly through interfering with the phosphorylation of Phospholipase C γ 1 (PLCG1) and Linker for Activation of T Cells (LAT) . This PTP was also found to dephosphorylate PDGF β receptor, and may be involved in UV-induced signal transduction.