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Product Description
XBP1 Antibody | XW-7785 | ProSci
Host: Chicken
Reactivity: Human
Homology: N/A
Immunogen: 130-261
Research Area: Other
Tested Application: WB
Application: X box-binding protein 1 antibody can be used for the detection of X box-binding protein 1 by Western Blot.
Specificiy: N/A
Positive Control 1: N/A
Positive Control 2: N/A
Positive Control 3: N/A
Positive Control 4: N/A
Positive Control 5: N/A
Positive Control 6: N/A
Molecular Weight: 28.7 kDa (calculated)
Validation: N/A
Isoform: N/A
Purification: Immunoaffinity Purified
Clonality: Polyclonal
Clone: N/A
Isotype: N/A
Conjugate: Unconjugated
Physical State: Liquid
Buffer: Phosphate-Buffered Saline. No preservatives added.
Concentration: 1 mg/mL
Storage Condition: XBP1 antibody can be stored at 4˚C for short term (weeks) . Long term storage should be at -20˚C. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Alternate Name: TREB5, XBP2, X-box-binding protein 1, Tax-responsive element-binding protein 5, XBP-1, TREB5, X boxbinding protein 1
User Note: Optimal dilutions for each application to be determined by the researcher.
BACKGROUND: FUNCTION: Transcription factor essential for hepatocyte growth, the differentiation of plasma cells, the immunoglobulin secretion, and the unfolded protein response (UPR) . Acts during endoplasmic reticulum stress (ER) by activating unfolded protein response (UPR) target genes via direct binding to the UPR element (UPRE) . Binds DNA preferably to the CRE-like element 5'-GATGACGTG[TG]N (3) [AT]T-3', and also to some TPA response elements (TRE) . Binds to the HLA DR-α promoter. Binds to the tax-responsive element (TRE) of HTLV-I.
