Product Description
PDGFR beta Antibody | 18-555 | ProSci
Host: Rabbit
Reactivity: Human, Mouse, Rat
Homology: N/A
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 887-1106 of human PDGFR beta (NP_002600.1) .
Research Area: Cancer, Cell Cycle, Growth Factors, Immunology, Signal Transduction
Tested Application: WB, IHC, IF
Application: WB: 1:500 - 1:2000
IHC: 1:50 - 1:200
IF: 1:50 - 1:200
Specificiy: N/A
Positive Control 1: SH-SY5Y
Positive Control 2: mouse lung
Positive Control 3: NIH/3T3
Positive Control 4: C2C12
Positive Control 5: N/A
Positive Control 6: N/A
Molecular Weight: Observed: 200kDa
Validation: N/A
Isoform: N/A
Purification: Affinity purification
Clonality: Polyclonal
Clone: N/A
Isotype: IgG
Conjugate: Unconjugated
Physical State: Liquid
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Concentration: N/A
Storage Condition: Store at -20˚C. Avoid freeze / thaw cycles.
Alternate Name: PDGFRB, CD140B, Beta pdfgr, Beta type PDGFR, BPDGFR, CD140b antigen, IBGC4, JTK12, PDGF-beta R, PDGF-R-beta, PDGFR, PDGFRbeta, PDGF receptor beta, PDGF-R, PDGFbetaR, PDGFR Beta, PDGFR-1, PDGFR-beta, BetaPDGFR, Pdgf beta-receptor, PDGFR1, PDGFRB/CEV14 fusion gene
User Note: Optimal dilutions for each application to be determined by the researcher.
BACKGROUND: This gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. This gene is flanked on chromosome 5 by the genes for granulocyte-macrophage colony-stimulating factor and macrophage-colony stimulating factor receptor; all three genes may be implicated in the 5-q syndrome. A translocation between chromosomes 5 and 12, that fuses this gene to that of the translocation, ETV6, leukemia gene, results in chronic myeloproliferative disorder with eosinophilia.