Product Description
PRLR Antibody | 13-700 | ProSci
Host: Rabbit
Reactivity: Human, Mouse, Rat
Homology: N/A
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 25-234 of human PRLR (NP_000940.1) .
Research Area: Apoptosis, Cell Cycle, Growth Factors, Signal Transduction
Tested Application: WB
Application: WB: 1:1000 - 1:2000
Specificiy: N/A
Positive Control 1: 293T
Positive Control 2: MCF7
Positive Control 3: Mouse ovary
Positive Control 4: N/A
Positive Control 5: N/A
Positive Control 6: N/A
Molecular Weight: Observed: 70kDa
Validation: N/A
Isoform: N/A
Purification: Affinity purification
Clonality: Polyclonal
Clone: N/A
Isotype: IgG
Conjugate: Unconjugated
Physical State: Liquid
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Concentration: N/A
Storage Condition: Store at -20˚C. Avoid freeze / thaw cycles.
Alternate Name: PRLR, HPRL receptor, PRL-R, HPRLrI, Prolactin receptor
User Note: Optimal dilutions for each application to be determined by the researcher.
BACKGROUND: This gene encodes a receptor for the anterior pituitary hormone, prolactin, and belongs to the type I cytokine receptor family. Prolactin-dependent signaling occurs as the result of ligand-induced dimerization of the prolactin receptor. Several alternatively spliced transcript variants encoding different membrane-bound and soluble isoforms have been described for this gene, which may function to modulate the endocrine and autocrine effects of prolactin in normal tissue and cancer.