Product Description
TCR beta Antibody [H57-597] | 77-207 | ProSci
Host: Hamster
Reactivity: Mouse
Homology: N/A
Immunogen: N/A
Research Area: Immunology, Functional Assays
Tested Application: Flow, Func, IHC, IF, IP
Application: N/A
Specificiy: The H57-597 monoclonal antibody is specific for the beta chain of the mouse T cell Receptor (TCR) .
Positive Control 1: N/A
Positive Control 2: N/A
Positive Control 3: N/A
Positive Control 4: N/A
Positive Control 5: N/A
Positive Control 6: N/A
Molecular Weight: N/A
Validation: N/A
Isoform: N/A
Purification: The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
Clonality: Monoclonal
Clone: H57-597
Isotype: Armenian Hamster IgG
Conjugate: Unconjugated
Physical State: liquid
Buffer: Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
Concentration: batch dependent
Storage Condition: The product should be stored undiluted at 4˚C and should be protected from prolonged exposure to light. Do not freeze.
Alternate Name: Tib, TCRbeta, Tcrb
User Note: Optimal dilutions for each application to be determined by the researcher.
BACKGROUND: The H57-597 monoclonal antibody is specific for the beta chain of the mouse T cell Receptor (TCR) . The crosslinking induces activation and proliferation of T cells, as a plate-bound or a soluble H57-597, or the plate-bound antibody can induce apoptosis, based on assay conditions. The beta chain of the TCR can combine with the alpha chain of the receptor to produce the alpha-beta TCR, which is expressed by the NKT cells, by the NK1.1+ thymocytes and most of the T cells. The beta chain does not react with the gamma-delta TCR-bearing cells, expressed by a small number of T cells. This antibody can be used as a phenotypic marker for the TCR beta expressing cells or for the functional purpose of TCR-mediated cell activation or apoptosis.