Product Description
TCR beta Antibody [H57-597] (FITC) | 98-899 | ProSci
Host: Hamster
Reactivity: Mouse
Homology: N/A
Immunogen: TCR affinity purified from mouse T-cell hybridoma DO-11.10
Research Area: Immunology
Tested Application: Flow
Application: TCR beta Antibody [H57-597] for use in flow cytometry and immunohistochemistry / immunocytochemistry assays.
Specificiy: TCRbeta
Positive Control 1: N/A
Positive Control 2: N/A
Positive Control 3: N/A
Positive Control 4: N/A
Positive Control 5: N/A
Positive Control 6: N/A
Molecular Weight: N/A
Validation: N/A
Isoform: N/A
Purification: N/A
Clonality: Monoclonal
Clone: [H57-597]
Isotype: IgG
Conjugate: FITC
Physical State: Liquid
Buffer: Supplied in PBS/NaN3
Concentration: 0.5 mg/mL
Storage Condition: Store vial at 2-8˚C
Alternate Name: N/A
User Note: Optimal dilutions for each application to be determined by the researcher.
BACKGROUND: The alphabeta TCR is expressed on T lymphocytes of all mouse strains tested. The H57-597 monoclonal antibody does not react with gammadelta TCR-bearing cells. Plate-bound or soluble H57-597 activates alphabeta TCR-bearing T cells. In vitro and in vivo, H57-597 can induce immature thymocytes to undergo apoptosis. In vivo administration of H57-597 has been shown to deplete alphabeta TCR-bearing cells to near completion and prevent graft rejection.