Product Description
ADAMTSL5 Antibody | 5687 | ProSci
Host: Chicken
Reactivity: Human, Mouse, Rat
Homology: N/A
Immunogen: ADAMTSL5 antibody was raised against a 17 amino acid synthetic peptide near the carboxy terminus of human ADAMTSL5.
The immunogen is located within the last 50 amino acids of ADAMTSL5.
Research Area: Homeostasis
Tested Application: E, WB, IHC-P, IF
Application: ADAMTSL5 antibody can be used for detection of ADAMTSL5 by Western blot at 1 μg/mL. Antibody can also be used for immunohistochemistry starting at 5 μg/mL. For immunofluorescence start at 20 μg/mL.
Antibody validated: Western Blot in human samples; Immunohistochemistry in mouse samples and Immunofluorescence in mouse samples. All other applications and species not yet tested.
Specificiy: N/A
Positive Control 1: Cat. No. 1375 - Human Skeletal Muscle Tissue Lysate
Positive Control 2: N/A
Positive Control 3: N/A
Positive Control 4: N/A
Positive Control 5: N/A
Positive Control 6: N/A
Molecular Weight: N/A
Validation: N/A
Isoform: N/A
Purification: ADAMTSL5 Antibody is affinity chromatography purified via peptide column.
Clonality: Polyclonal
Clone: N/A
Isotype: IgY
Conjugate: Unconjugated
Physical State: Liquid
Buffer: ADAMTSL5 Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration: 1 mg/mL
Storage Condition: ADAMTSL5 antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Alternate Name: ADAMTSL5 Antibody: THSD6, THSD6, ADAMTS-like protein 5, Thrombospondin type-1 domain-containing protein 6, ADAMTSL-5
User Note: Optimal dilutions for each application to be determined by the researcher.
BACKGROUND: ADAMTSL5 Antibody: ADAMTSL5 belongs to a large superfamily containing 20 ADAMTS proteases and at least eight ADAMTS-like proteins. ADAMTS proteases are secreted enzymes with a conserved organization that includes a metalloprotease domain and an ancillary domain containing one or more thrombospondin type 1 repeats (TSR) . The ADAMTS-like subfamily comprises proteins homologous to the ADAMTS ancillary domains but lacking the protease domain and hence lacking catalytic activity. The exact role of ADAMTSL5 is currently unknown, but other ADAMTS-like proteins appear to have regulatory roles in the extracellular matrix.