Product Description
KCNK1 Antibody | 8017 | ProSci
Host: Rabbit
Reactivity: Human, Mouse, Rat
Homology: Predicted species reactivity based on immunogen sequence: Rabbit: (100%) , Bovine: (100%) , Guinea pig: (100%)
Immunogen: KCNK1 antibody was raised against a 17 amino acid peptide near the carboxy terminus of human KCNK1.
The immunogen is located within amino acids 220 - 270 of KCNK1.
Research Area: Neuroscience
Tested Application: E, WB, IHC-P, IF
Application: KCNK1 antibody can be used for detection of KCNK1 by Western blot at 1 - 2 μg/ml. Antibody can also be used for immunohistochemistry starting at 5 μg/mL. For immunofluorescence start at 20 μg/mL.
Antibody validated: Western Blot in mouse samples; Immunohistochemistry in mouse samples and Immunofluorescence in mouse samples. All other applications and species not yet tested.
Specificiy: KCNK1 antibody is human, mouse and rat reactive. KCNK1 antibody is predicted to not cross-react with other KCNK proteins.
Positive Control 1: Cat. No. 1212 - 3T3 Cell Lysate
Positive Control 2: N/A
Positive Control 3: N/A
Positive Control 4: N/A
Positive Control 5: N/A
Positive Control 6: N/A
Molecular Weight: Predicted: 37 kDa
Observed: 35 kDa
Validation: N/A
Isoform: N/A
Purification: KCNK1 antibody is affinity chromatography purified via peptide column.
Clonality: Polyclonal
Clone: N/A
Isotype: IgG
Conjugate: Unconjugated
Physical State: Liquid
Buffer: KCNK1 antibody is supplied in PBS containing 0.02% sodium azide.
Concentration: 1 mg/mL
Storage Condition: KCNK1 antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year.
Alternate Name: Potassium channel subfamily K member 1, DPK, HOHO, K2P1, K2p1.1, KCNO1, TWIK-1, TWIK1
User Note: Optimal dilutions for each application to be determined by the researcher.
BACKGROUND: The potassium channel, subfamily K, member 1 (KCNK1) , is member of the superfamily of potassium channel proteins containing two pore-forming P domains (1, 2) . KCNK1 is a ubiquitous human weakly inward rectifying K+ channel that is widely expressed in human tissues, and particularly abundant in brain and heart (1) . Both KCNK1 and the related protein KCNK2 contribute significantly to the passive conductance of hippocampal astrocytes (3) .