Product Description
PLAC4 Antibody | 6021 | ProSci
Host: Rabbit
Reactivity: Human
Homology: N/A
Immunogen: PLAC4 antibody was raised against a 17 amino acid synthetic peptide near the center of human PLAC4.
The immunogen is located within amino acids 20 - 70 of PLAC4.
Research Area: Cancer, Cell Cycle
Tested Application: E, WB, ICC, IF
Application: PLAC4 antibody can be used for detection of PLAC4 by Western blot at 1 - 2 μg/mL. Antibody can also be used for immunocytochemistry starting at 10 μg/mL. For immunofluorescence start at 20 μg/mL.
Antibody validated: Western Blot in human samples; Immunocytochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.
Specificiy: N/A
Positive Control 1: Cat. No. 1309 - Human Placenta Tissue Lysate
Positive Control 2: Cat. No. 17-001 - HeLa Cell Slide
Positive Control 3: N/A
Positive Control 4: N/A
Positive Control 5: N/A
Positive Control 6: N/A
Molecular Weight: N/A
Validation: N/A
Isoform: N/A
Purification: PLAC4 Antibody is affinity chromatography purified via peptide column.
Clonality: Polyclonal
Clone: N/A
Isotype: IgG
Conjugate: Unconjugated
Physical State: Liquid
Buffer: PLAC4 Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration: 1 mg/mL
Storage Condition: PLAC4 antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Alternate Name: PLAC4 Antibody: PRED78, C21orf115, D21S418E, PP1416, Placenta-specific protein 4
User Note: Optimal dilutions for each application to be determined by the researcher.
BACKGROUND: PLAC4 Antibody: PLAC4 (placenta-specific protein 4) , was initially discovered as a gene whose mRNA was expressed in placental syncytiotrophoblast and choriocarcinoma cells. While the function of PLAC4 is currently unclear, its gene is known to be located on chromosome 21q22.3. Due to the PLAC4 gene location on chromosome 21 and the release of its mRNA transcripts into maternal bloodstream from the placenta, it has been proposed to be a useful marker noninvasive prenatal chromosome 21 aneuploidy detection, although other reports suggests that PLAC4 mRNA levels are not altered in the maternal circulation of pregnancies with trisomy 21.