Product Description
UBTD1 Antibody | 55-458 | ProSci
Host: Rabbit
Reactivity: Human
Homology: Predicted species reactivity based on immunogen sequence: Bovine, Mouse, Rat
Immunogen: This UBTD1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 180-212 amino acids from the C-terminal region of human UBTD1.
Research Area: Cell Cycle
Tested Application: WB, IHC-P
Application: For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:50
Specificiy: N/A
Positive Control 1: N/A
Positive Control 2: N/A
Positive Control 3: N/A
Positive Control 4: N/A
Positive Control 5: N/A
Positive Control 6: N/A
Molecular Weight: 26 kDa
Validation: N/A
Isoform: N/A
Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Clonality: Polyclonal
Clone: N/A
Isotype: Rabbit Ig
Conjugate: Unconjugated
Physical State: Liquid
Buffer: Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration: batch dependent
Storage Condition: Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Alternate Name: Ubiquitin domain-containing protein 1, UBTD1
User Note: Optimal dilutions for each application to be determined by the researcher.
BACKGROUND: UBTD1 contains a ubiquitin domain, and has been demonstrated to bind to p53 in cells p53 is linked to the ubiquitination pathway through its transcriptional regulation of the four ubiquitin ligases, MDM2, COP1, Siah1b, and Pirh2. The role of UBTD1 has not been elucidated, however preliminary evidence indicates a potential role in p53 signaling.