Product Description
MADCAM1 Antibody | 18-903 | ProSci
Host: Rabbit
Reactivity: Human, Mouse, Rat
Homology: N/A
Immunogen: A synthetic peptide of human MADCAM1
Research Area: Cell Cycle, Immunology, Innate Immunity, Neuroscience, Signal Transduction
Tested Application: WB, IHC
Application: WB: 1:200 - 1:1000
IHC: 1:50 - 1:100
Specificiy: N/A
Positive Control 1: SW480
Positive Control 2: SH-SY5Y
Positive Control 3: Jurkat
Positive Control 4: A-549
Positive Control 5: mouse spleen
Positive Control 6: rat spleen
Molecular Weight: Observed: 45kDa
Validation: N/A
Isoform: N/A
Purification: Affinity purification
Clonality: Polyclonal
Clone: N/A
Isotype: IgG
Conjugate: Unconjugated
Physical State: Liquid
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Concentration: N/A
Storage Condition: Store at -20˚C. Avoid freeze / thaw cycles.
Alternate Name: MADCAM1, HMAdCAM-1, MACAM1, MAdCAM-1
User Note: Optimal dilutions for each application to be determined by the researcher.
BACKGROUND: The protein encoded by this gene is an endothelial cell adhesion molecule that interacts preferentially with the leukocyte beta7 integrin LPAM-1 (alpha4beta7) , L-selectin, and VLA-4 (alpha4beta1) on myeloid cells to direct leukocytes into mucosal and inflamed tissues. It is a member of the immunoglobulin family and is similar to ICAM1 and VCAM1. At least seven alternatively spliced transcripts encoding different protein isoforms have been found for this gene, but the full-length nature of some variants has not been determined.